Lots of customers these days are installing big flat screens on the wall opposite the bed. They don;t want to see the cable box. So I put the cable box, fed from the source, on, or in, a piece of furniture or built-in, on a different wall of the bedroom. The incoming signal goes from the box, back down to the MDF, and back up to the TV on a different run.
This has all been changed recently, by the need for HDMI interconnection, though. Now, I run two Cat5e or one HDMI to each TV location, and don't run them as homeruns to the MDF, but rather just run them over to where the box will be placed. I use either rigid or flexible plastic tubing for that short(er) run, so the room is future-proofed.